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💊 Statin Dose Equivalency Calculator
⚠️ Disclaimer: This calculator uses ACC/AHA guideline-based intensity classifications and approximate LDL-C reduction ranges. Individual patient response varies significantly. Always consider renal function, drug interactions, tolerability, and specific guideline indications when selecting or switching statins. This tool is for educational reference only and does not replace clinical judgment.
Equivalent Intensity Statin Options
| Statin |
Equivalent Dose Options |
Intensity |
Expected LDL-C Reduction |
📊 About Intensity-Based Equivalency: This calculator uses ACC/AHA guideline intensity classifications. Statins are grouped by their ability to reduce LDL-C: Low intensity (<30%), Moderate intensity (30-49%), High intensity (≥50%). The specific LDL-C reduction percentages shown are approximations based on clinical trial data and may vary between individuals. Multiple dose options within the same intensity range are expected to provide clinically similar outcomes. Equivalency is conceptualized by intensity category, not by exact milligram-to-milligram conversion.
⚠️ Simvastatin 80 mg Safety Alert: The 80 mg dose is associated with increased risk of myopathy and rhabdomyolysis. It should only be continued in patients already stable on this dose for ≥12 months without muscle toxicity. It is NOT recommended for new starts or switches. Consider high-intensity alternatives (atorvastatin 40-80 mg or rosuvastatin 20-40 mg) instead.